Inside news May. However, the central nervous system is not a major site of MC1R expression. Under normal circumstances, when there is no mutation, the gene will bind and protect the skin from developing cancer cells. Pharmacology, Biochemistry and Behavior. Listen to our new podcast, 'The Last Continent'. Hoary stereotypes, such as the idea that redheads are also hot heads, are mixed together with actual physiological differences — such as a heightened sensitivity to pain.
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Demographic and morphometric data were similar in the groups Table 1. The human MC1R is expressed on the surface of melanocytes and is a key regulator of intracellular signaling to the melanin biosynthetic pathway governing pigment formation. Coupon Offers. The subjects fasted and refrained from smoking for at least eight hours before arriving at the laboratory.